About Sucraid®
Sucraid® is the only FDA-approved enzyme replacement therapy for the treatment of CSID.
About CSID
Congenital Sucrase-Isomaltase Deficiency (CSID), also known as Genetic Sucrase-Isomaltase Deficiency (GSID).
Patient Assistance
SucraidASSIST™ is a comprehensive support program that provides information and support.
What is Congenital Sucrase-Isomaltase Deficiency?
CSID is a disorder that reduces the effectiveness of enzymes that digest carbohydrates (sugar and starch). Congenital Sucrase-Isomaltase Deficiency, also known as Genetic Sucrase-Isomaltase Deficiency (GSID), is an inherited disorder that causes these digestive enzymes either to be missing or to not work as well.
Download the doctor discussion guide + Sucraid® 4-Day Trial Prescription Forms.
Talking to your doctor about CSID symptoms like bloating, gas, and diarrhea can be uncomfortable, but it’s crucial for an accurate diagnosis.
Prepare for your appointment with the CSID Doctor Discussion Guide. It helps you organize your symptoms, medical history, and questions for your doctor.
Click below to download the guide, fill it out, and share it with your doctor. Also, ask your GI specialist if you qualify for a 4-day trial of Sucraid®.
Enter your email to receive the latest updates on CSID and treatment options.
Download the doctor discussion guide + Sucraid® 4-Day Trial Prescription Forms.
Talking to your doctor about CSID symptoms like bloating, gas, and diarrhea can be uncomfortable, but it’s crucial for an accurate diagnosis.
Prepare for your appointment with the CSID Doctor Discussion Guide. It helps you organize your symptoms, medical history, and questions for your doctor.
Click below to download the guide, fill it out, and share it with your doctor. Also, ask your GI specialist if you qualify for a 4-day trial of Sucraid®.
Enter your email to receive the latest updates on CSID and treatment options.
See how Sucraid® works. Watch the Video
What is Sucraid®?
Sucraid® is the only FDA-approved drug for the treatment of genetically sucrase deficiency, which is part of Congenital Sucrase-Isomaltase Deficiency (CSID). Sucraid® is an enzyme replacement therapy, providing a substitute for the sucrase enzyme in the small intestine that is missing or not working in people who have CSID. CSID may also be called a form of Sucrose Intolerance, carbohydrate malabsorption or intolerance or Genetic Sucrase-Isomaltase Deficiency (GSID).
Effective
Patients who became asymptomatic* with Sucraid® in a clinical trial.1
*Study patients, who were diagnosed with CSID and took Sucraid® with each meal, were considered asymptomatic if they reported no GI symptoms for 7 of the 10 study days (N=26).
1 Treem WR, McAdams L, Standford L, Kastoff G, Justinich C, Hyams J. Sacrosidase Therapy for Congenital Sucrase-Isomaltase Deficiency. J Pediatr Gastroenterol Nutr. 1999;28(2):137-42. doi:10.1097/00005176-199902000-00008
Effective
Patients who became asymptomatic* with Sucraid® in a clinical trial.1
*Study patients, who were diagnosed with CSID and took Sucraid® with each meal, were considered asymptomatic if they reported no GI symptoms for 7 of the 10 study days (N=26).
1 Treem WR, McAdams L, Standford L, Kastoff G, Justinich C, Hyams J. Sacrosidase Therapy for Congenital Sucrase-Isomaltase Deficiency. J Pediatr Gastroenterol Nutr. 1999;28(2):137-42. doi:10.1097/00005176-199902000-00008
Sucraid® is a drug that is only available by prescription, but a prescription for Sucraid® cannot be filled by your corner drugstore. The only way to get a Sucraid® prescription filled is through the specialty pharmacy. Call the specialty pharmacy at 1-833-800-0122.
If your doctor has prescribed Sucraid® for you, it is because you have been diagnosed with CSID. If that is the case, your doctor wishes to determine if a trial of Sucraid® therapy would help relieve some of your GI symptoms.
- Sucraid® 2 mL is supplied in single-use containers packaged in a foil pouch
- Each mL of solution contains 8,500 international units (IU) of sacrosidase
- Each foil pouch includes five Sucraid® single-use containers
Patient Stories
For us, Sucraid® is the difference between strict diet adherence and a more normal diet. Sucraid® means more freedom of choice for us.”
Aileen, Caregiver for Patient Treated With Sucraid®
These statements reflect individual experiences and should not be used as a substitute for talking with your doctor about whether Sucraid® is right for you. Your doctor can discuss the benefits and risks with you. Each patient experience is unique and QOL Medical, LLC does not provide any warranty or guarantee as to the response a patient will have to Sucraid®.
Insights
An enzyme is a naturally-occurring protein that makes the chemical reactions that occur all the time in the body, occur much faster.
We rely on the enzymes our body produces to help the tissues and organs in our body function normally. Sucrase is the enzyme that helps our body digest sucrose, which is a fancy name for white table sugar.
Sucrose is a complex sugar called a disaccharide, created by the combination of two simple sugars (monosaccharides), glucose and fructose.
Sucrose is mainly found in plants and is the primary component of most granulated sugars we use in baking. It’s commonly known as white table sugar and/or brown sugar, or just sugar. These sugars are mostly refined from sugar beets or sugar cane. Today, sucrose can be found in a range of commercially prepared foods like cookies, ice cream, candy, crackers, and cured meats. Sucrose is also found naturally in many fresh fruits.
Sucraid facilitates the breakdown of the complex sugar (sucrose) into its simpler forms, enabling the absorption of the simple sugars from the small intestine into the bloodstream where it can be used by the tissues and organs in the body as a source of energy. In clinical studies of CSID patients, sacrosidase, the active ingredient in Sucraid, was shown to provide significant relief for most patients of the gastrointestinal (GI) symptoms associated with CSID. Sucraid can help affected individuals maintain a more normal diet that can include foods that contain sucrose.
Scientific words sometimes use the same ending to identify various compounds that all belong to the same, specific category.
For example, the names for various sugars all end in “ose,” such as glucose, fructose, lactose, and sucrose. The names for various enzymes often begin with the name for the compound they affect and all end in “ase,” such as lactase, which breaks down lactose; protease, which breaks down proteins; lipase, which breaks down lipids (fats); and sucrase, which breaks down sucrose.
Carbohydrates are one of the three main sources of nutrients in our diets.
The other two are proteins and lipids (fats). Carbohydrates are made by plants to store energy. They are complex compounds that must be broken down to a simpler form before they can be absorbed into the bloodstream.
There are three types of carbohydrates. Sugars are simple or complex carbohydrates, found in white table sugar, baked goods, fruits, vegetables, and dairy products. Starches are made up of more than one sugar unit bound together and are found in whole grains, potatoes, pasta, vegetables, and beans. Dietary fiber is a very complex carbohydrate that your body cannot digest, so it passes through the intestine undigested. Fiber is a food source for the “good” bacteria that exist naturally in your large intestine. Fiber is present in fruits, vegetables, legumes, nuts, seeds, and whole grains.
If you think you may have CSID, it is recommended that you schedule a visit to discuss your concerns with a gastroenterologist.
Watch Now
Behind the Mystery: Rare & Genetic Diseases is a special video on the balancing act of treating individuals who have CSID. This is an interview with Dr. William Treem, a pediatric gastroenterologist who has studied and treated patients with CSID for years.
QOL Medical contributed financially to the production and air time of this video, which appeared on the Lifetime Television Network. Dr. William Treem, who appears in this video, was a paid consultant of QOL Medical and was compensated for his time participating in this video. Please see the indication and important safety information for Sucraid® below.