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IMPORTANT SAFETY INFORMATION

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Important Safety Information for Sucraid® (sacrosidase) Oral Solution

  • Sucraid® may cause a serious allergic reaction. If you notice any swelling or have difficulty breathing, get emergency help right away.
  • Tell your doctor if you are allergic to, have ever had a reaction to, or have ever had difficulty taking yeast, yeast products, papain, or glycerin (glycerol).
  • Sucraid® does not break down some sugars that come from the digestion of starch. You may need to restrict the amount of starch in your diet. Your doctor will tell you if you should restrict starch in your diet.
  • Tell your doctor if you have diabetes, as your blood glucose levels may change if you begin taking Sucraid®. Your doctor will tell you if your diet or diabetes medicines need to be changed.
  • Some patients treated with Sucraid® may have worse abdominal pain, vomiting, nausea, or diarrhea. Constipation, difficulty sleeping, headache, nervousness, and dehydration have also occurred in patients treated with Sucraid®. Check with your doctor if you notice these or other side effects.
  • Sucraid® has not been tested to see if it works in patients with secondary (acquired) sucrase deficiency.
  • NEVER HEAT SUCRAID® OR PUT IT IN WARM OR HOT BEVERAGES OR INFANT FORMULA. Do not mix Sucraid® with fruit juice or take it with fruit juice. Take Sucraid® as prescribed by your doctor. Normally, half of the dose of Sucraid® is taken just before a meal or snack and the other half is taken during the meal or snack.
  • Sucraid® should be refrigerated at 36°F-46°F (2°C-8°C) and should be protected from heat and light; single-use containers can be removed from refrigeration and stored at 59°F-77°F (15°C-25°C) for up to 3 days (72 hours).

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.FDA.gov/medwatch or call 1-800-FDA-1088.

Indication

Sucraid® (sacrosidase) Oral Solution is an enzyme replacement therapy for the treatment of genetically determined sucrase deficiency, which is part of Congenital Sucrase-Isomaltase Deficiency (CSID).

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IMPORTANT SAFETY INFORMATION

IMPORTANT SAFETY INFORMATION:

Could it be CSID
Could It Be CSID?

You’ve Heard of Lactose Intolerance and Gluten Intolerance.

CSID is characterized by the inability to digest and absorb sugar.1

Congenital Sucrase-Isomaltase Deficiency (CSID) is a rare, inherited disease that causes Sucrose Intolerance.1

Learn More

  1. Treem WR, McAdams L, Stanford L, Kastoff G, Justinich C, Hyams J. Sacrosidase therapy for congenital sucrase-isomaltase deficiency. J Pediatr Gastroenterol Nutr. 1999;28(2):137-42. doi:10.1097/00005176-199902000-00008
CSID Common Symptoms
CSID Common Symptoms

CSID symptoms to look for.

CSID symptoms commonly are mistaken for other GI issues (eg, IBS).1-3

You should consider CSID if you think you might be experiencing IBS but are not responding to treatment. With CSID, GI symptoms have usually been a problem for a very long time (since childhood or for many years) and may occur more frequently after meals.4

  • Watery Diarrhea
  • Bloating
  • Excess Gas Production
  • Abdominal Pain
  • Nausea
  • Vomiting

How to Diagnose

  1. Henström M, Diekmann L, Bonfiglio F, et al. Functional variants in the sucrase-isomaltase gene associate with increased risk of irritable bowel syndrome. Gut. 2018;67(2):263-270. doi:10.1136/gutjnl-2016-312456
  2. Garcia-Etxebarria K, Zheng T, Bonfiglio F, et al. Increased prevalence of rare sucrase-isomaltase pathogenic variants in irritable bowel syndrome patients. Clin Gastroenterol Hepatol. 2018;16(10):1673-76. doi:10.1016/j.cgh.2018.01.047
  3. Kim SB, Calmet FH, Garrido J, Garcia-Buitrago MT, Moshiree B. Sucrase-isomaltase deficiency as a potential masquerader in irritable bowel syndrome. Dig Dis Sci. 2020;65(2):534-540. doi:10.1007/s10620-019-05780-7
  4. Treem WR. Clinical aspects and treatment of congenital sucrase-isomaltase deficiency. J Pediatr Gastroenterol Nutr. 2012;55(suppl 2):S7-13. doi: 10.1097/01.mpg.0000421401.57633.9
Sucraid® Treats CSID
Sucraid® Treats CSID

Help alleviate CSID symptoms with Sucraid®.1

The only FDA-approved enzyme replacement therapy indicated for the treatment of sucrase deficiency due to Congenital Sucrase-Isomaltase Deficiency (CSID).1

In a clinical trial, 81% of CSID patients treated with Sucraid® became asymptomatic.*

How to Order

  1. Treem WR, McAdams L, Stanford L, Kastoff G, Justinich C, Hyams J. Sacrosidase therapy for congenital sucrase-isomaltase deficiency. J Pediatr Gastroenterol Nutr. 1999;28(2):137-42. doi:10.1097/00005176-199902000-00008

* Patients who took Sucraid® with each meal were considered asymptomatic if they reported no GI symptoms for at least 7 of the 10 study days.

How Sucraid® Works
How Sucraid® Works

Sucraid®: The mechanism of action.

The active ingredient in Sucraid® is sacrosidase, which is a sucrase enzyme replacement. It splits sucrose into glucose and fructose, which facilitates absorption of both into the bloodstream from the small intestine.1

Learn More

  1. Sucraid® [package insert]. Vero Beach, FL: QOL Medical, LLC; 2023.
Doctor Discussion Guide
Doctor Discussion Guide

Download resources for CSID and Sucraid®.

Download

Important Safety Information for Sucraid® (sacrosidase) Oral Solution

  • Sucraid® may cause a serious allergic reaction. If you notice any swelling or have difficulty breathing, get emergency help right away.
  • Tell your doctor if you are allergic to, have ever had a reaction to, or have ever had difficulty taking yeast, yeast products, papain, or glycerin (glycerol).
  • Sucraid® does not break down some sugars that come from the digestion of starch. You may need to restrict the amount of starch in your diet. Your doctor will tell you if you should restrict starch in your diet.
  • Tell your doctor if you have diabetes, as your blood glucose levels may change if you begin taking Sucraid®. Your doctor will tell you if your diet or diabetes medicines need to be changed.
  • Some patients treated with Sucraid® may have worse abdominal pain, vomiting, nausea, or diarrhea. Constipation, difficulty sleeping, headache, nervousness, and dehydration have also occurred in patients treated with Sucraid®. Check with your doctor if you notice these or other side effects.
  • Sucraid® has not been tested to see if it works in patients with secondary (acquired) sucrase deficiency.
  • NEVER HEAT SUCRAID® OR PUT IT IN WARM OR HOT BEVERAGES OR INFANT FORMULA. Do not mix Sucraid® with fruit juice or take it with fruit juice. Take Sucraid® as prescribed by your doctor. Normally, half of the dose of Sucraid® is taken just before a meal or snack and the other half is taken during the meal or snack.
  • Sucraid® should be refrigerated at 36°F-46°F (2°C-8°C) and should be protected from heat and light; single-use containers can be removed from refrigeration and stored at 59°F-77°F (15°C-25°C) for up to 3 days (72 hours).

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.FDA.gov/medwatch or call 1-800-FDA-1088.

Indication

Sucraid® (sacrosidase) Oral Solution is an enzyme replacement therapy for the treatment of genetically determined sucrase deficiency, which is part of Congenital Sucrase-Isomaltase Deficiency (CSID).